Metabolic Syndrome Model Definitions Predicting Type 2 Diabetes and Cardiovascular Disease

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Metabolic Syndrome Model Definitions Predicting Type 2 Diabetes and Cardiovascular Disease

OBJECTIVE Metabolic syndrome (MetS) is a cluster of abdominal obesity, hyperglycemia, hypertension, and dyslipidemia, which increases the risk for type 2 diabetes and cardiovascular diseases (CVDs). Some argue that MetS is not a single disorder because the traditional MetS features do not represent one entity, and they would like to exclude features from MetS. Others would like to add additiona...

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The metabolic syndrome: validity and utility of clinical definitions for cardiovascular disease and diabetes risk prediction.

The purpose of clinical definitions of the metabolic syndrome is frequently misunderstood. While the metabolic syndrome as a physiological process describes a clustering of numerous age-related metabolic abnormalities that together increase the risk for cardiovascular disease and type 2 diabetes, clinical definitions include obesity which is thought to be a cause rather than a consequence of me...

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Metabolic syndrome and subsequent risk of type 2 diabetes and cardiovascular disease in elderly women

The prognostic value of the metabolic syndrome (MetS) is believed to vary with age. With an elderly population expecting to triple by 2060, it is important to evaluate the validity of MetS in this age group. We examined the association of MetS risk factors with later risk of type 2 diabetes (T2DM) and cardiovascular disease (CVD) in elderly Caucasian women. We further investigated if stratifica...

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Metabolic syndrome as a precursor of cardiovascular disease and type 2 diabetes mellitus.

BACKGROUND The incidence of cardiovascular disease (CVD), coronary heart disease (CHD), and type 2 diabetes mellitus (T2DM) has not been well defined in persons with the metabolic syndrome (at least 3 of the following: abdominal adiposity, low HDL cholesterol, high triglycerides, hypertension, and impaired fasting glucose). The objective was to investigate risk for CVD, CHD, and T2DM according ...

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The Metabolic Syndrome as a Risk Factor for Type 2 Diabetes and Cardiovascular Disease

This paper discusses the prevalence and clinical significance of the metabolic syndrome and considers the importance of lipid and lipoprotein abnormalities in the metabolic syndrome in conferring cardiovascular and metabolic risk. The metabolic syndrome is a multiplex risk factor for cardiovascular and metabolic disease. Cardinal components of the metabolic syndrome include obesity (particularl...

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ژورنال

عنوان ژورنال: Diabetes Care

سال: 2012

ISSN: 0149-5992,1935-5548

DOI: 10.2337/dc11-2546